Omics in the Foreseeable Future
Nebert DW, Jorge-Nebert L, Vesell ES. Pharmacogenomics and "Individualized Drug Therapy": high expectations and disappointing achievements. Am J Pharmacogenomics. 3(6):361-70. (only abstract available for free)
Genomics is an important tool in basic research; yet, it is unrealistic to include genotyping within the realm of tests available to the practicing clinician in the foreseeable future. The same can be said for transcriptomics and proteomics…The newly emerging fields of metabonomics and phenomics might offer solutions to anticipating and decreasing individual risk for adverse drug reactions in each individual patient; however, tests based on these approaches are not expected to become available to the practicing clinician for at least the next 5-10 years.