siRNA Libraries

"Sometimes the first step to learning a gene’s role is to disable it and see what happens. Now researchers at the Stanford University School of Medicine have devised a new way of halting gene expression that is both fast and cheap enough to make the technique practical for widespread use. This work will accelerate efforts to find genes that are involved in cancer and the fate of stem cells, or to find genes that make good targets for therapeutic drugs."

Press Release, Gene-Disabling Technique Simplified by Stanford Team. Jan 13 2004.  This group has developed a method for creating siRNA libraries.  Here is a flash animation showing a mechanism for RNA interference or RNAi.  In the animation, the little red pieces labeled "guide sequeces" are short interfering RNA or siRNA.

February 15, 2004 | Filed Under science 

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