Your microbiota is SOOOO agnotobiotic
Cheap personal microbiomics will make the
human microbiota gnotobiotic! It just rolls off the tongue (an
decreasingly agnotobiotic human organ). Does all this verbage leave a bad taste in your mouth?
Microbiota: The collection of micro-organisms in a particular environment, such as the human body, e.g. the human gut microbiota.
Microbiome: The collection of genetic material (all the genomes) in a particular microbiota.
Gnotobiotic: Describes a microbiota with a known set of micro-organisms.
Agnotobiotic: Describes a microbiota of unknown or poorly defined composition.
Here are some stats to cleanse your palate:
- 10 billion bacteria per ml of saliva (with 700 or more species in the oral cavity)
- 100 billion micro-organisms per ml of material in the human colon
- 1 trillion bacteria on the human skin (2 square meters total of human skin)
- 10 trillion human cells in our bodies
- 100 trillion micro-organisms in the human gastrointestinal tract
We are born relatively germ-free. Its unknown the extent to which we acquire our microbiomes from family members, but this may be another type of genetic heritability. In this case, genetics is definitely not destiny. We will increasingly be learning how to "reprogram" our microbiomes.
Microbiota management, flora farming, bug doping. Oh My!
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Additional reading and references below the jump.

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